PICOT Clinical Trial

Each year more than 100,000 Australians experience a road traffic injury, the majority (75 percent) are considered non-catastrophic neck and back injuries. Up to 50 percent of people do not recover but develop chronic pain (pain that persists more than 3 months). This represents a significant health burden for Australia.

A biopsychosocial approach to care is recommended, and our previous clinical trial showed that when physiotherapists include psychological strategies as part of their treatment (StressModex intervention), recovery improves. However, this approach is not used routinely in Australia, with a major barrier being limited training and lack confidence of physiotherapists to deliver psychological care.

Our earlier clinical trial showed that 2 days in-person training improved patient outcomes. In-person training is difficult to scale, limiting widespread implementation and sustainable change in clinical practice.

To address this barrier, with our partners, we developed a novel online implementation strategy: Physiotherapists bIopsyChosocial Online Training (PICOT) to implement the StressModex intervention.

Contact

    Aims

    Funded by the Medical Research Future Fund, Professor Michele Sterling and team will compare the effectiveness of in-person training versus an online training program for physiotherapists delivering the StressModex intervention to people suffering from non-catastrophic road traffic injury. The main aims are to compare the:

    1. Effectiveness of the two implementation strategies (in-person training versus PICOT) for the delivery of StressModex in routine physiotherapy practice;
    2. Effectiveness of the two implementation strategies on patient outcomes; and
    3. Cost-effectiveness of the two implementation strategies. 
    Top of page

    Progress

    The PICOT trial's set-up is well underway and we've completed the following milestones:

    • Ethics approval
    • Protocol
    • Governance
    • Consumer Advisory Group
    • Redcap database
    • Training curriculum
    • Physiotherapist clinic recruitment
    • Physiotherapist training of StressModex

    Approximately 36 physiotherapy clinics across all Australian states and the Australian Capital Territory are taking part in this trial.

    Physiotherapists completed their training as of early April 2025 and have begun participant recruitment at their respective clinics and delivering StressModex to clients with whiplash.

    Top of page

    Research Team

    Coordinating Principal Investigator

    Professor Michele Sterling, The University of Queensland 

    Clinical Trial Coordinators

    Dr Yanfei Xie, The University of Queensland

    Dr Christopher Papic, The University of Queensland

    Chief Investigators

    Professor Michele Sterling, The University of Queensland

    Dr Rachel Elphinston, The University of Queensland

    Dr Roma Forbes, The University of Queensland

    Professor Nadine Foster, The University of Queensland/STARS Research and Education Alliance

    Associate Professor Jason Lodge, The University of Queensland

    Dr Johanna Lynch, The University of Queensland

    Associate Professor Shaun O'Leary, The University of Queensland

    Dr Kerry Peek, The University of Sydney

    Dr Jenny Setchell, The University of Queensland

    Professor Helen Slater, Curtin University

    Dr Julia Treleaven, The University of Queensland

    Associate Professor Haitham Tuffaha, The University of Queensland

    Associate Investigators

    Tim Austin, The University of Sydney

    David Brentnall, Axis Rehab

    Professor Simon French, Macquarie University

    Dr Kerrie Evans, The University of Sydney/Allsports Physiotherapy

    Professor Michael Nicholas, Northern Sydney Local Health District

    Professor Trudy Rebbeck, The University of Sydney

    Professor Robert Ware, Griffith University

    Research Assistant

    Ms Chloe-Emily Eather, The University of Queensland

    Data Manager

    Ms Maryrose Malt, The University of Queensland

    Trial Administrator

    Dr William McCann, The University of Queensland

    Top of page

    Funding Partners